Recombinant HA-based vaccine outperforms split and subunit vaccines in elicitation of influenza-specific CD4 T cells and CD4 T cell-dependent antibody responses in humans

Richards, KA; Moritzky, S; Shannon, I; Fitzgerald, T; Yang, H; Branche, A; Topham, DJ; Treanor, JJ; Nayak, J; Sant, AJ

Sant, AJ (corresponding author), Univ Rochester, David H Smith Ctr Vaccine Biol & Immunol, Dept Microbiol & Immunol, Med Ctr, 601 Elmwood AveBox 609, Rochester, NY 14642 USA.

NPJ VACCINES, 2020; 5 (1):

Abstract

Although traditional egg-based inactivated influenza vaccines can protect against infection, there have been significant efforts to develop improved f......

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