Differences in Liver TFAM Binding to mtDNA and mtDNA Damage between Aged and Extremely Aged Rats

Chimienti, G; Picca, A; Fracasso, F; Marzetti, E; Calvani, R; Leeuwenburgh, C; Russo, F; Lezza, AMS; Pesce, V

Pesce, V (reprint author), Univ Bari Aldo Moro, Dept Biosci Biotechnol & Biopharmaceut, I-70125 Bari, Italy.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2019; 20 (10):

Abstract

While mitochondrial dysfunction is acknowledged as a major feature of aging, much less is known about the role of mitochondria in extended longevity. ......

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