Targeting Pin1 by inhibitor API-1 regulates microRNA biogenesis and suppresses hepatocellular carcinoma development

Pu, WC; Li, J; Zheng, YY; Shen, XY; Fan, X; Zhou, JK; He, J; Deng, YL; Liu, XS; Wang, C; Yang, SY; Chen, Q; Liu, LX; Zhang, GL; Wei, YQ; Peng, Y

Peng, Y (reprint author), Sichuan Univ, State Key Lab Biotherapy, West China Hosp, Renmin South Rd,Sect 3-17, Chengdu 610041, Sichuan, Peoples R China.

HEPATOLOGY, 2018; 68 (2): 547

Abstract

Hepatocellular carcinoma (HCC) is a leading cause of cancer death worldwide, but there are few effective treatments. Aberrant microRNA (miRNA) biogene......

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