A Regulatory Loop of FBXW7-MYC-PLK1 Controls Tumorigenesis of MYC-Driven Medulloblastoma

Wang, D; Pierce, A; Veo, B; Fosmire, S; Danis, E; Donson, A; Venkataraman, S; Vibhakar, R

Vibhakar, R (corresponding author), Univ Colorado, Dept Pediat, Anschutz Med Campus, Aurora, CO 80045 USA.; Vibhakar, R (corresponding author), Childrens Hosp Colorado, Morgan Adams Fdn, Pediat Brain Tumor Res Program, Aurora, CO 80045 USA.; Vibhakar, R (corresponding author), Univ Colorado Denver, Dept Neurosurg, Aurora, CO 80045 USA.

CANCERS, 2021; 13 (3):

Abstract

Simple Summary Group 3 medulloblastoma (MB) is often accompanied by MYC amplification and has a poor prognosis. FBXW7, a critical tumor suppressor in ......

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