Targeting a Proteinase-Activated Receptor 4 (PAR4) Carboxyl Terminal Motif to Regulate Platelet Function

Ramachandran, R; Mihara, K; Thibeault, P; Vanderboor, CM; Petri, B; Saifeddine, M; Bouvier, M; Hollenberg, MD

Ramachandran, R (reprint author), Univ Western Ontario, Schulich Sch Med & Dent, Dept Physiol & Pharmacol, MSB 270,1151 Richmond St, London, ON N6A 5C1, Canada.

MOLECULAR PHARMACOLOGY, 2017; 91 (4): 287

Abstract

Thrombin initiates human platelet aggregation by coordinately activating proteinase-activated receptors (PARs) 1 and 4. However, targeting PAR1 with a......

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