Blockade of spinal dopamine D1/D2 receptor suppresses activation of NMDA receptor through Gaq and Src kinase to attenuate chronic bone cancer pain

Dai, WL; Bao, YN; Fan, JF; Ma, B; Li, SS; Zhao, WL; Yu, BY; Liu, JH

Yu, BY; Liu, JH (corresponding author), China Pharmaceut Univ, Jiangsu Key Lab TCM Evaluat & Translat Res, Sch Tradit Chinese Pharm, Nanjing 211198, Jiangsu, Peoples R China.

JOURNAL OF ADVANCED RESEARCH, 2021; 28 (): 139

Abstract

Introduction: Spinal N-methyl-D-aspartate receptor (NMDAR) is vital in chronic pain, while NMDAR antagonists have severe side effects. NMDAR has been ......

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