IONIS-PKKRx a Novel Antisense Inhibitor of Prekallikrein and Bradykinin Production

Ferrone, JD; Bhattacharjee, G; Revenko, AS; Zanardi, TA; Warren, MS; Derosier, FJ; Viney, NJ; Pham, NC; Kaeser, GE; Baker, BF; Schneider, E; Hughes, SG; Monia, BP; MacLeod, AR

MacLeod, AR (reprint author), Ionis Pharmaceut Inc, 2855 Gazelle Court, Carlsbad, CA 92010 USA.

NUCLEIC ACID THERAPEUTICS, 2019; 29 (2): 82

Abstract

Kallikrein is the key contact system mediator responsible for the conversion of high-molecular-weight kininogen into the inflammatory vasodilator pept......

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