Activation of 4-1BB signaling in bone marrow stromal cells triggers bone loss via the p-38 MAPK-DKK1 axis in aged mice

Wan, DQ; Ai, ST; Ouyang, HN; Cheng, LM

Cheng, LM (corresponding author), Tongji Univ, Sch Med, Tongji Hosp, Dept Orthoped, Shanghai, Peoples R China.; Cheng, LM (corresponding author), Minist Educ Peoples Republ China, Key Lab Spine & Spinal Cord Injury Repair & Regen, Shanghai, Peoples R China.; Ouyang, HN (corresponding author), Shanghai Jiao Tong Univ, Sch Med, Shanghai Peoples Hosp 9, Dept Neurosurg, Shanghai, Peoples R China.

EXPERIMENTAL AND MOLECULAR MEDICINE, 2021; 53 (4): 654

Abstract

Senile osteoporosis can cause bone fragility and increased fracture risks and has been one of the most prevalent and severe diseases affecting the eld......

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