CBFB-MYH11 Fusion Sequesters RUNX1 in Cytoplasm to Prevent DNMT3A Recruitment to Target Genes in AML

Liu, P; Liu, JP; Sun, SJ; Gao, Y; Ai, YJ; Chen, XF; Sun, YP; Zhou, MY; Liu, Y; Xiong, Y; Yuan, HX

Yuan, HX (corresponding author), Fudan Univ, Peoples Hosp Shanghai 5, Shanghai, Peoples R China.; Yuan, HX (corresponding author), Fudan Univ, Inst Biomed Sci, Mol & Cell Biol Res Lab, Shanghai, Peoples R China.

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2021; 9 ():

Abstract

A growing number of human diseases have been found to be associated with aberrant DNA methylation, including cancer. Mutations targeting genes encodin......

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