JAK2-V617F promotes venous thrombosis through beta(1)/beta(2) integrin activation

Edelmann, B; Gupta, N; Schnoeder, TM; Oelschlegel, AM; Shahzad, K; Goldschmidt, J; Philipsen, L; Weinert, S; Ghosh, A; Saalfeld, FC; Nimmagadda, SC; Muller, P; Braun-Dullaeus, R; Mohr, J; Wolleschak, D; Kliche, S; Amthauer, H; Heidel, FH; Schraven, B

Fischer, T (reprint author), Otto von Guericke Univ, Med Ctr, Ctr Internal Med, Dept Hematol & Oncol, Leipzigerstr 44, D-39120 Magdeburg, Germany.

JOURNAL OF CLINICAL INVESTIGATION, 2018; 128 (10): 4359

Abstract

JAK2-V617F-positive chronic myeloproliferative neoplasia (CMN) commonly displays dysfunction of integrins and adhesion molecules expressed on platelet......

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