Wwp2 maintains cartilage homeostasis through regulation of Adamts5

Mokuda, S; Nakamichi, R; Matsuzaki, T; Ito, Y; Sato, T; Miyata, K; Inui, M; Olmer, M; Sugiyama, E; Lotz, M; Asahara, H

Asahara, H (reprint author), Scripps Res Inst, Dept Mol Med, 10550 North Torrey Pines Rd, La Jolla, CA 92037 USA.; Asahara, H (reprint author), TMDU, Grad Sch Med & Dent Sci, Dept Syst BioMed, Bunkyo Ku, 1-5-45 Yushima, Tokyo 1138510, Japan.

NATURE COMMUNICATIONS, 2019; 10 ():

Abstract

The WW domain-containing protein 2 (Wwp2) gene, the host gene of miR-140, codes for the Wwp2 protein, which is an HECT-type E3 ubiquitin ligases abund......

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