PAD4 takes charge during neutrophil activation: Impact of PAD4 mediated NET formation on immune-mediated disease

Liu, XS; Arfman, T; Wichapong, K; Reutelingsperger, CPM; Voorberg, J; Nicolaes, GAF

Nicolaes, GAF (corresponding author), Maastricht Univ, Cardiovasc Res Inst Maastricht CARIM, Dept Biochem, POB 616, NL-6200 MD Maastricht, Netherlands.

JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2021; 19 (7): 1607

Abstract

Background: Peptidyl arginine deiminase 4 (PAD4) is an enzyme that converts arginine into citrulline. PAD4 is expressed in neutrophils that, when acti......

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