THADA fusion is a mechanism of IGF2BP3 activation and IGF1R signaling in thyroid cancer

Panebianco, F; Kelly, LM; Liu, PY; Zhong, S; Dacic, S; Wang, XS; Singhi, AD; Dhir, R; Chiosea, SI; Kuan, SF; Bhargava, R; Dabbs, D; Trivedi, S; Gandhi, M; Diaz, R; Wald, AI; Carty, SE; Ferris, RL; Lee, AV; Nikiforova, MN; Nikiforov, YE

Nikiforov, YE (reprint author), Univ Pittsburgh, Sch Med, Dept Pathol & Lab Med, Pittsburgh, PA 15213 USA.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2017; 114 (9): 2307

Abstract

Thyroid cancer development is driven by known point mutations or gene fusions found in similar to 90% of cases, whereas driver mutations in the remain......

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