CD8(+)PD-1(+) to CD4(+)PD-1(+) ratio (PERLS) is associated with prognosis of patients with advanced NSCLC treated with PD-(L)1 blockers-MedSci.cn

CD8(+)PD-1(+) to CD4(+)PD-1(+) ratio (PERLS) is associated with prognosis of patients with advanced NSCLC treated with PD-(L)1 blockers

Duchemann, B; Naigeon, M; Auclin, E; Ferrara, R; Cassard, L; Jouniaux, JM; Boselli, L; Grivel, J; Desnoyer, A; Danlos, FX; Mezquita, L; Caramella, C; Marabelle, A; Besse, B; Chaput, N

Chaput, N (通讯作者)，Gustave Roussy, US23, INSERM, Lab Immunomonitoring Oncol,CNRS,UMS 3655, Villejuif, Ile De France, France.;Chaput, N (通讯作者)，Univ Paris Saclay, Fac Pharm, Chatenay Malabry, Ile De France, France.

Abstract

Background Programmed cell death protein-1 (PD-1) expression has been associated with activation and exhaustion of both the CD4 and CD8 populations in......

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CD8(+)PD-1(+) to CD4(+)PD-1(+) ratio (PERLS) is associated with prognosis of patients with advanced NSCLC treated with PD-(L)1 blockers

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