Toll-like receptor 7 deficiency protects apolipoprotein E-deficient mice from diet-induced atherosclerosis

Liu, CL; Santos, MM; Fernandes, C; Liao, MY; Iamarene, K; Zhang, JY; Sukhova, GK; Shi, GP

Shi, GP (reprint author), Zhengzhou Univ, Affiliated Hosp 1, Inst Clin Med, Dept Cardiol, Zhengzhou, Peoples R China.; Shi, GP (reprint author), Brigham & Womens Hosp, Dept Med, Boston, MA 02115 USA.; Shi, GP (reprint author), Harvard Med Sch, Boston, MA

SCIENTIFIC REPORTS, 2017; 7 ( ):

Abstract

Toll-like receptor 7 (TLR7) mediates autoantigen and viral RNA-induced cytokine production. Increased TLR7 expression in human atherosclerotic lesions......

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