Human RAD52 Captures and Holds DNA Strands, Increases DNA Flexibility, and Prevents Melting of Duplex DNA: Implications for DNA Recombination

Brouwer, I; Zhang, H; Candelli, A; Normanno, D; Peterman, EJG; Wuite, GJL; Modesti, M

Peterman, EJG; Wuite, GJL (reprint author), Vrije Univ Amsterdam, Dept Phys & Astron, NL-1081 HV Amsterdam, Netherlands.; Modesti, M (reprint author), Vrije Univ Amsterdam, Laser Lab, NL-1081 HV Amsterdam, Netherlands.

CELL REPORTS, 2017; 18 (12): 2845

Abstract

Human RAD52 promotes annealing of complementary single-stranded DNA (ssDNA). In-depth knowledge of RAD52-DNA interaction is required to understand how......

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