Minimally invasive quantification of cerebral P2X7R occupancy using dynamic [F-18]JNJ-64413739 PET and MRA-driven image derived input function

Mertens, N; Schmidt, ME; Hijzen, A; Van Weehaeghe, D; Ravenstijn, P; Depre, M; de Hoon, J; Van Laere, K; Koole, M

Mertens, N (corresponding author), Univ Hosp, Dept Imaging & Pathol, Nucl Med & Mol Imaging, Herestr 49, B-3000 Leuven, Belgium.; Mertens, N (corresponding author), Katholieke Univ Leuven, Herestr 49, B-3000 Leuven, Belgium.

SCIENTIFIC REPORTS, 2021; 11 (1):

Abstract

[F-18]JNJ-64413739 has been evaluated as PET-ligand for in vivo quantification of purinergic receptor subtype 7 receptor (P2X7R) using Logan graphical......

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