Structural basis of specific H2A K13/K15 ubiquitination by RNF168

Horn, V; Uckelmann, M; Zhang, HY; Eerland, J; Aarsman, I; le Paige, UB; Davidovich, C; Sixma, TK; van Ingen, H

van Ingen, H (reprint author), Leiden Univ, Leiden Inst Chem, Dept Macromol Biochem, POB 95022300 RA, Leiden, Netherlands.; Sixma, TK (reprint author), Netherlands Canc Inst, Div Biochem, POB 902031006 BE, Amsterdam, Netherlands.; Sixma, TK (reprint autho

NATURE COMMUNICATIONS, 2019; 10 ():

Abstract

Ubiquitination of chromatin by modification of histone H2A is a critical step in both regulation of DNA repair and regulation of cell fate. These very......

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