C/EBP alpha and GATA-2 Mutations Induce Bilineage Acute Erythroid Leukemia through Transformation of a Neomorphic Neutrophil-Erythroid Progenitor

Di Genua, C; Valletta, S; Buono, M; Stoilova, B; Sweeney, C; Rodriguez-Meira, A; Grover, A; Drissen, R; Meng, YR; Beveridge, R; Aboukhalil, Z; Karamitros, D; Belderbos, ME; Bystrykh, L; Thongjuea, S; Vyas, P; Nerlov, C

Nerlov, C (corresponding author), Univ Oxford, John Radcliffe Hosp, MRC Weatherall Inst Mol Med, MRC Mol Haematol Unit, Oxford OX3 9DS, England.

CANCER CELL, 2020; 37 (5): 690

Abstract

Acute erythroid leukemia (AEL) commonly involves both myeloid and erythroid lineage transformation. However, the mutations that cause AEL and the cell......

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