Substrate rigidity dictates colorectal tumorigenic cell stemness and metastasis via CRAD-dependent mechanotransduction

Chang, YH; Zhang, J; Huo, XY; Qu, XL; Xia, CL; Huang, KZ; Xie, FY; Wang, NF; Wei, XW; Jia, Q

Wei, XW; Jia, Q (通讯作者),Nanjing Med Univ, Nanjing Hosp 1, Dept Oncol, Nanjing 210006, Peoples R China.

CELL REPORTS, 2022; 38 (7):

Abstract

Tumor physical microenvironment contributes greatly to the response of tumor cells. However, the mechanism of how extracellular substrate rigidity rem......

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