Butyrate Protects Mice from Clostridium difficile-Induced Colitis through an HIF-1-Dependent Mechanism

Fachi, JL; Felipe, JD; Pral, LP; da Silva, BK; Correa, RO; de Andrade, MCP; da Fonseca, DM; Basso, PJ; Camara, NOS; Souza, ELDE; Martins, FD; Guima, SES; Thomas, AM; Setubal, JC; Magalhaes, YT; Forti, FL; Candreva, T; Rodrigues, HG; de Jesus, MB; Con

Vinolo, MAR (reprint author), Univ Estadual Campinas, Inst Biol, Dept Genet Evolut Microbiol & Immunol, Lab Immunoinflammat, BR-13083862 Campinas, SP, Brazil.

CELL REPORTS, 2019; 27 (3): 750

Abstract

Antibiotic-induced dysbiosis is a key factor predisposing intestinal infection by Clostridium difficile. Here, we show that interventions that restore......

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