Intracellular localisation of Mycobacterium tuberculosis affects efficacy of the antibiotic pyrazinamide

Santucci, P; Greenwood, DJ; Fearns, A; Chen, K; Jiang, HB; Gutierrez, MG

Gutierrez, MG (corresponding author), Francis Crick Inst, Host Pathogen Interact TB Lab, London, England.; Jiang, HB (corresponding author), Univ Western Australia, Sch Mol Sci, Perth, WA, Australia.; Jiang, HB (corresponding author), Univ Hong Kong, Dept Chem, Hong Kong, Peoples R China.

NATURE COMMUNICATIONS, 2021; 12 (1):

Abstract

To be effective, chemotherapy against tuberculosis (TB) must kill the intracellular population of the pathogen, Mycobacterium tuberculosis. However, h......

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