MDM2 Antagonist Idasanutlin Reduces HDAC1/2 Abundance and Corepressor Partners but Not HDAC3

Smalley, JP; Cowley, SM; Hodgkinson, JT

Hodgkinson, JT (通讯作者)，Univ Leicester, Leicester Inst Struct & Chem Biol, Sch Chem, Leicester LE1 7RH, England.;Cowley, SM (通讯作者)，Univ Leicester, Dept Mol & Cell Biol, Leicester LE1 7RH, England.

ACS MEDICINAL CHEMISTRY LETTERS, 2023; 15 (1): 93

Abstract

Histone deacetylases 1-3 (HDAC1, HDAC2, and HDAC3) and their associated corepressor complexes play important roles in regulating chromatin structure a......

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