The Functional Roles of the MDM2 Splice Variants P2-MDM2-10 and MDM2-Delta 5 in Breast Cancer Cells

Huun, J; Gansmo, LB; Mannsaker, B; Iversen, GT; Sommerfelt-Pettersen, J; Ovrebo, JI; Lonning, PE; Knappskog, S

Knappskog, S (reprint author), Univ Bergen, Sect Oncol, Dept Clin Sci, N-5020 Bergen, Norway.

TRANSLATIONAL ONCOLOGY, 2017; 10 (5): 806

Abstract

BACKGROUND: MDM2 is a negative regulator of p53 and is upregulated in numerous human cancers. While different MDM2 splice variants have been observed ......

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