Opposing Roles of FANCJ and HLTF Protect Forks and Restrain Replication during Stress

Peng, M; Cong, K; Panzarino, NJ; Nayak, S; Calvo, J; Deng, B; Zhu, LJ; Morocz, M; Hegedus, L; Haracska, L; Cantor, SB

Cantor, SB (reprint author), Univ Massachusetts, Sch Med, Dept Mol Cell & Canc Biol, Worcester, MA 01605 USA.

CELL REPORTS, 2018; 24 (12): 3251

Abstract

The DNA helicase FANCJ is mutated in hereditary breast and ovarian cancer and Fanconi anemia (FA). Nevertheless, how loss of FANCJ translates to disea......

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