Carboxymethyl chitosan prolongs adenovirus-mediated expression of IL-10 and ameliorates hepatic fibrosis in a mouse model

Gou, YN; Weng, YG; Chen, Q; Wu, JH; Wang, H; Zhong, JM; Bi, Y; Cao, DG; Zhao, PA; Dong, XY; Guo, MC; Wagstaff, W; Hendren-Santiago, B; Chen, C; Youssef, A; Haydon, RC; Luu, HH; Reid, RR; Shen, L; He, TC; Fan, JM

He, TC; Fan, JM (通讯作者)，Univ Chicago, Mol Oncol Lab, Med Ctr, Chicago, IL 60637 USA.;Fan, JM (通讯作者)，Chongqing Med Univ, Sch Lab Med, Dept Clin Biochem, Minist Educ,Key Lab Diagnost Med, Chongqing 400016, Peoples R China.

BIOENGINEERING & TRANSLATIONAL MEDICINE, 2022; 7 (3):

Abstract

Effective and safe liver-directed gene therapy has great promise in treating a broad range of liver diseases. While adenoviral (Ad) vectors have been ......

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