Neratinib protects pancreatic beta cells in diabetes

Ardestani, A; Li, SJ; Annamalai, K; Lupse, B; Gerayandi, S; Dobrowolski, A; Yu, S; Zhu, SY; Baguley, TD; Surakattula, M; Oetjen, J; Hauberg-Lotte, L; Herranz, R; Awal, S; Altenhofen, D; Van, NT; Joseph, S; Schultz, PG; Chatterjee, AK; Rogers, N; Trem

Ardestani, A; Maedler, K (reprint author), Univ Bremen, Ctr Biomol Interact Bremen, Bremen, Germany.; Tremblay, MS; Shen, WJ (reprint author), Calibr, Scripps Res, La Jolla, CA 92037 USA.

NATURE COMMUNICATIONS, 2019; 10 ():

Abstract

The loss of functional insulin-producing beta-cells is a hallmark of diabetes. Mammalian sterile 20-like kinase 1 (MST1) is a key regulator of pancrea......

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