Western-style diet consumption impairs maternal insulin sensitivity and glucose metabolism during pregnancy in a Japanese macaque model

Elsakr, JM; Zhao, SK; Ricciardi, V; Dean, TA; Takahashi, DL; Sullivan, E; Wesolowski, SR; McCurdy, CE; Kievit, P; Friedman, JE; Aagaard, KM; Edwards, DRV; Gannon, M

Gannon, M (corresponding author), Vanderbilt Univ, Dept Mol Physiol & Biophys, Nashville, TN 37232 USA.; Edwards, DRV (corresponding author), Vanderbilt Univ, Med Ctr, Dept Obstet & Gynecol, Div Quantitat Sci, 2525 West End Ave,Suite 600, Nashville, TN 37203 USA.; Gannon, M (corresponding author), Vanderbilt Univ, Med Ctr, Dept Med, Div Diabet Endocrinol & Metab, 2213 Garland Ave,7465 MRBIV, Nashville, TN 37232 USA.; Edwards, DRV (corresponding author), Vanderbilt Univ, Med Ctr, Dept Obstet & Gy

SCIENTIFIC REPORTS, 2021; 11 (1):

Abstract

The prevalence of maternal obesity is increasing in the United States. Offspring born to women with obesity or poor glycemic control have greater odds......

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