DEC2 modulates orexin expression and regulates sleep

Hirano, A; Hsu, PK; Zhang, LY; Xing, LJ; McMahon, T; Yamazaki, M; Ptacek, LJ; Fu, YH

Ptacek, LJ; Fu, YH (reprint author), Univ Calif San Francisco, Dept Neurol, San Francisco, CA 94143 USA.; Ptacek, LJ; Fu, YH (reprint author), Univ Calif San Francisco, Weill Neurosci Inst, San Francisco, CA 94143 USA.; Ptacek, LJ; Fu, YH (reprint author)

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2018; 115 (13): 3434

Abstract

Adequate sleep is essential for physical and mental health. We previously identified a missense mutation in the human DEC2 gene (BHLHE41) leading to t......

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