Directing Nanoparticle Biodistribution through Evasion and Exploitation of Stab2-Dependent Nanoparticle Uptake

Campbell, F; Bos, FL; Sieber, S; Arias-Alpizar, G; Koch, BE; Huwyler, J; Kros, A; Bussmann, J

Campbell, F; Kros, A; Bussmann, J (reprint author), Leiden Univ, Leiden Inst Chem, Dept Supramol & Biomat Chem, POB 9502, NL-2300 RA Leiden, Netherlands.; Bussmann, J (reprint author), Leiden Univ, Inst Biol Leiden, Dept Mol Cell Biol, POB 9502, NL-2300 R

ACS NANO, 2018; 12 (3): 2138

Abstract

Up to 99% of systemically administered nanoparticles are cleared through the liver. Within the liver, most nanoparticles are thought to be sequestered......

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