Identification of small molecules that mitigate vincristine-induced neurotoxicity while sensitizing leukemia cells to vincristine

Diouf, B; Wing, C; Panetta, JC; Eddins, D; Lin, WW; Yang, WJ; Fan, YP; Pei, DQ; Cheng, C; Delaney, SM; Zhang, W; Bonten, EJ; Crews, KR; Paugh, SW; Li, L; Freeman, BB; Autry, RJ; Beard, JA; Ferguson, DC; Janke, LJ; Ness, KK; Chen, TS; Zakharenko, SS; Jeha, S; Pui, CH; Relling, MV; Dolan, ME; Evans, WE

Evans, WE (corresponding author), St Jude Childrens Res Hosp, 262 Danny Thomas Pl, Memphis, TN 38105 USA.

CTS-CLINICAL AND TRANSLATIONAL SCIENCE, 2021; 14 (4): 1490

Abstract

Vincristine (VCR) is one of the most widely prescribed medications for treating solid tumors and acute lymphoblastic leukemia (ALL) in children and ad......

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