Inhibition of GATA2 restrains cell proliferation and enhances apoptosis and chemotherapy mediated apoptosis in human GATA2 overexpressing AML cells

Menendez-Gonzalez, JB; Sinnadurai, S; Gibbs, A; Thomas, LA; Konstantinou, M; Garcia-Valverde, A; Boyer, M; Wang, ZK; Boyd, AS; Blair, A; Morgan, RG; Rodrigues, NP

Rodrigues, NP (reprint author), Cardiff Univ, Sch Biosci, European Canc Stem Cell Res Inst, Hadyn Ellis Bldg, Cardiff CF24 4HQ, S Glam, Wales.

SCIENTIFIC REPORTS, 2019; 9 ():

Abstract

GATA2, a zinc finger transcription factor predominantly expressed in hematopoietic cells, acts as an essential regulator of hematopoietic stem cell ge......

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