The molecular basis of JAK/STAT inhibition by SOCS1

Liau, NPD; Laktyushin, A; Lucet, IS; Murphy, JM; Yao, S; Whitlock, E; Callaghan, K; Nicola, NA; Kershaw, NJ; Babon, JJ

Kershaw, NJ; Babon, JJ (reprint author), Walter & Eliza Hall Inst Med Res, 1G Royal Parade, Parkville, Vic 3052, Australia.; Kershaw, NJ; Babon, JJ (reprint author), Univ Melbourne, Parkville, Vic 3050, Australia.

NATURE COMMUNICATIONS, 2018; 9 ():

Abstract

The SOCS family of proteins are negative-feedback inhibitors of signalling induced by cytokines that act via the JAK/STAT pathway. SOCS proteins can a......

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