Association of 5-FU Therapeutic Drug Monitoring to DPD Phenotype Assessment May Reduce 5-FU Under-Exposure

Dolat, M; Macaire, P; Goirand, F; Vincent, J; Hennequin, A; Palmier, R; Bengrine-Lefevre, L; Ghiringhelli, F; Royer, B; Schmitt, A

PHARMACEUTICALS, 2020; 13 (11):

Abstract

In order to limit 5-fluorouracil (5-FU) toxicity, some health agencies recommend evaluating dihydropyrimidine dehydrogenase (DPD) deficiency before an......

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