Generation of a new mouse model of glaucoma characterized by reduced expression of the AP-2 beta and AP-2 delta proteins

Barzago, MM; Kurosaki, M; Fratelli, M; Bolis, M; Giudice, C; Nordio, L; Cerri, E; Domenici, L; Terao, M; Garattini, E

Terao, M; Garattini, E (reprint author), IRCCS Ist Ric Farmacol Mario Negri, Mol Biol Lab, Via La Masa 19, I-20156 Milan, Italy.

SCIENTIFIC REPORTS, 2017; 7 ( ):

Abstract

We generated 6 transgenic lines with insertion of an expression plasmid for the R883/M xanthine dehydrogenase (XDH) mutant protein. Approximately 20% ......

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