Targeting IS608 transposon integration to highly specific sequences by structure-based transposon engineering

Morero, NR; Zuliani, C; Kumar, B; Bebel, A; Okamoto, S; Guynet, C; Hickman, AB; Chandler, M; Dyda, F; Barabas, O

Barabas, O (reprint author), European Mol Biol Lab, Struct & Computat Biol Unit, D-69117 Heidelberg, Germany.; Dyda, F (reprint author), NIDDK, Lab Mol Biol, NIH, Bethesda, MD 20892 USA.

NUCLEIC ACIDS RESEARCH, 2018; 46 (8): 4152

Abstract

Transposable elements are efficient DNA carriers and thus important tools for transgenesis and insertional mutagenesis. However, their poor target seq......

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