MGMT: Immunohistochemical Detection in High-Grade Astrocytomas

Lipp, ES; Healy, P; Austin, A; Clark, A; Dalton, T; Perkinson, K; Herndon, JE; Friedman, HS; Friedman, AH; Bigner, DD; McLendon, RE

Lipp, ES (reprint author), Duke Univ, Med Ctr, Preston Robert Tisch Brain Tumor Ctr, POB 3624,Room 047,Baker House, Durham, NC 27710 USA.

JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY, 2019; 78 (1): 57

Abstract

Glioma therapeutic resistance to alkylating chemotherapy is mediated via O6-methylguanine-DNA methyltransferase (MGMT). We hypothesized that a CD45/HA......

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