A feedback loop engaging propionate catabolism intermediates controls mitochondrial morphology

Zhou, JX; Duan, M; Wang, X; Zhang, FX; Zhou, HJ; Ma, TF; Yin, QY; Zhang, J; Tian, F; Wang, GD; Yang, CL

Duan, M; Yang, CL (通讯作者)，Yunnan Univ, Sch Life Sci, Ctr Life Sci, State Key Lab Conservat & Utilizat Bioresources, Kunming, Yunnan, Peoples R China.

NATURE CELL BIOLOGY, 2022; 24 (4): 526

Abstract

d-2-Hydroxyglutarate (D-2HG) is an alpha-ketoglutarate-derived mitochondrial metabolite that causes d-2-hydroxyglutaric aciduria, a devastating develo......

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