Molecular Mechanisms of PARP-1 Inhibitor 7-Methylguanine

Nilov, D; Maluchenko, N; Kurgina, T; Pushkarev, S; Lys, A; Kutuzov, M; Gerasimova, N; Feofanov, A; Svedas, V; Lavrik, O; Studitsky, VM

Nilov, D (corresponding author), Lomonosov Moscow State Univ, Belozersky Inst Physicochem Biol, Lenin Hills 1,Bldg 40, Moscow 119991, Russia.; Studitsky, VM (corresponding author), Lomonosov Moscow State Univ, Fac Biol, Lenin Hills 1,Bldg 12, Moscow 119992, Russia.; Studitsky, VM (corresponding author), Fox Chase Canc Ctr, Cottman Ave 333, Philadelphia, PA 19111 USA.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020; 21 (6):

Abstract

7-Methylguanine (7-MG), a natural compound that inhibits DNA repair enzyme poly(ADP-ribose) polymerase 1 (PARP-1), can be considered as a potential an......

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