Cannabidiol inhibits Nav channels through two distinct binding sites

Huang, J; Fan, X; Jin, XQ; Jo, S; Zhang, HB; Fujita, A; Bean, BP; Yan, N

Yan, N (通讯作者)，Princeton Univ, Dept Mol Biol, Princeton, NJ 08544 USA.;Yan, N (通讯作者)，Tsinghua Univ, Beijing Frontier Res Ctr Biol Struct, Tsinghua Peking Joint Ctr Life Sci, Sch Life Sci,State Key Lab Membrane Biol, Beijing 100084, Peoples R China.;Bean, BP (通讯作者)，Harvard Med Sch, Dept Neurobiol, 220 Longwood Ave, Boston, MA 02115 USA.

NATURE COMMUNICATIONS, 2023; 14 (1):

Abstract

Cannabidiol (CBD), a major non-psychoactive phytocannabinoid in cannabis, is an effective treatment for some forms of epilepsy and pain. At high conce......

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