Brahma Related Gene 1 (Brg1) Regulates Cellular Cholesterol Synthesis by Acting as a Co-factor for SREBP2

Fan, ZW; Kong, M; Li, M; Hong, WX; Fan, XS; Xu, Y

Fan, XS (corresponding author), Nanjing Univ, Dept Pathol, Med Sch, Nanjing Drum Tower Hosp, Nanjing, Peoples R China.; Xu, Y (corresponding author), Nanjing Med Univ, Key Lab Targeted Intervent Cardiovasc Dis, Dept Pathophysiol, Nanjing, Peoples R China.; Xu, Y (corresponding author), Nanjing Med Univ, Collaborat Innovat Ctr Cardiovasc Translat Med, Dept Pathophysiol, Nanjing, Peoples R China.; Xu, Y (corresponding author), Liaocheng Univ, Inst Biomed Res, Liaocheng, Shandong, Peoples R China.

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2020; 8 ():

Abstract

Hepatocyte is a hub for cholesterol metabolism. Augmented synthesis of cholesterol in the liver is associated with hypercholesterolemia and contribute......

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