DNA sensing in cancer: Pro-tumour and anti-tumour functions of cGAS-STING signalling

Wheeler, OPG; Unterholzner, L

Unterholzner, L (通讯作者),Univ Lancaster, Fac Hlth & Med, Div Biomed & Life Sci, Lancaster, England.

ESSAYS IN BIOCHEMISTRY, 2023; 67 (6): 905

Abstract

The DNA sensor cGAS (cyclic GMP-AMP synthase) and its adaptor protein STING (Stimulator of Interferon Genes) detect the presence of cytosolic DNA as a......

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