Fructose-1,6-bisphosphatase 1 functions as a protein phosphatase to dephosphorylate histone H3 and suppresses PPAR alpha-regulated gene transcription and tumour growth

Wang, Z; Li, M; Jiang, HF; Luo, SD; Shao, F; Xia, Y; Yang, MK; Ren, XL; Liu, T; Yan, MS; Qian, X; He, HY; Guo, D; Duan, YR; Wu, K; Wang, L; Ji, GM; Shen, YL; Li, L; Zheng, PX; Dong, BF; Fang, J; Zheng, M; Liang, TB; Li, HT; Yu, RL; Xu, DQ; Lu, ZM

Xu, DQ; Lu, ZM (通讯作者)，Zhejiang Univ, Sch Med, Affiliated Hosp 1, Zhejiang Prov Key Lab Pancreat Dis, Hangzhou, Peoples R China.;Xu, DQ; Lu, ZM (通讯作者)，Zhejiang Univ, Sch Med, Inst Translat Med, Hangzhou, Peoples R China.;Xu, DQ; Lu, ZM (通讯作者)，Zhejiang Univ, Canc Ctr, Hangzhou, Peoples R China.

NATURE CELL BIOLOGY, 2022; 24 (11): 1655

Abstract

Tumour cells exhibit greater metabolic plasticity than normal cells and possess selective advantages for survival and proliferation with unclearly def......

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