Validated HPLC method for simultaneous quantification of mutant IDH1/2 inhibitors (enasidenib, ivosidenib and vorasidenib) in mouse plasma: Application to a pharmacokinetic study

Zakkula, A; Dittakavi, S; Maniyar, MM; Syed, N; Sulochana, SP; Zainuddin, M; Mullangi, R

Mullangi, R (reprint author), Jubilant Biosys Ltd, Drug Metab & Pharmacokinet, Bangalore 560022, Karnataka, India.

BIOMEDICAL CHROMATOGRAPHY, 2019; 33 (11):

Abstract

Isocitrate dehydrogenase (IDH) inhibitors comprise a novel class of anticancer drugs, which are approved to treat acute myeloid leukemia patients havi......

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