Histone Demethylase KDM4C Stimulates the Proliferation of Prostate Cancer Cells via Activation of AKT and c-Myc

Lin, CY; Wang, BJ; Chen, BC; Tseng, JC; Jiang, SS; Tsai, KK; Shen, YY; Yuh, CH; Sie, ZL; Wang, WC; Kung, HJ; Chuu, CP

Chuu, CP (reprint author), Natl Hlth Res Inst, Inst Cellular & Syst Med, Miaoli 35053, Taiwan.; Chuu, CP (reprint author), China Med Univ, Grad Program Aging, Taichung 404, Taiwan.; Chuu, CP (reprint author), China Med Univ, Grad Inst Basic Med Sci, Taich

CANCERS, 2019; 11 (11):

Abstract

Our three-dimensional organotypic culture revealed that human histone demethylase (KDM) 4C, a histone lysine demethylase, hindered the acini morphogen......

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