5-ALA Is a Potent Lactate Dehydrogenase Inhibitor but Not a Substrate: Implications for Cell Glycolysis and New Avenues in 5-ALA-Mediated Anticancer Action

Grigalavicius, M; Ezzatpanah, S; Papakyriakou, A; Raabe, TTH; Yannakopoulou, K; Theodossiou, TA

Theodossiou, TA (通讯作者),Oslo Univ Hosp, Inst Canc Res, Dept Radiat Biol, N-0379 Oslo, Norway.

CANCERS, 2022; 14 (16):

Abstract

In a course of metabolic experiments, we determined that the addition of b-aminolevulinic acid (5-ALA) to a panel of glioblastoma multiforme (GBM) cel......

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