Introduction of fluorine atoms to vitamin D-3 side-chain and synthesis of 24, 24-difluoro-25-hydroxyvitamin D-3

Kawagoe, F; Mototani, S; Yasuda, K; Nagasawa, K; Uesugi, M; Sakaki, T; Kittaka, A

Kittaka, A (reprint author), Teikyo Univ, Fac Pharmaceut Sci, Itabashi Ku, 2-11-1 Kaga, Tokyo 1738605, Japan.

JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 2019; 195 ():

Abstract

During our ongoing studies of vitamin D, we focused on the vitamin D-3 side-chain 24-position, which is the major metabolic site of human CYP24A1. In ......

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