Novel Ocellatin Peptides Mitigate LPS-induced ROS Formation and NF-kB Activation in Microglia and Hippocampal Neurons

Sousa, NA; Oliveira, GAL; de Oliveira, AP; Lopes, ALF; Iles, B; Nogueira, KM; Araujo, TSL; Souza, LKM; Araujo, AR; Ramos-Jesus, J; Placido, A; Amaral, C; Campelo, YDM; Barbosa, EA; Portugal, CC; Socodato, R; Lobo, A; Relvas, J; Bemquerer, M; Eaton, P; Leite, JRSA; Medeiros, JVR

Medeiros, JVR (corresponding author), Univ Fed Delta Parnaiba, Lab Farmacol Inflamacao & Doencas Gastrintestinai, UFDPar, Piaui, Brazil.; Medeiros, JVR (corresponding author), Univ Fed Piaui, UFPI, Nucleo Pesquisa Biodiversidade & Biotecnol, Piaui, Brazil.

SCIENTIFIC REPORTS, 2020; 10 (1):

Abstract

Cutaneous secretions of amphibians have bioactive compounds, such as peptides, with potential for biotechnological applications. Therefore, this study......

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