Inhibitory affinity modulation of Fc gamma RIIA ligand binding by glycosphingolipids by inside-out signaling

Okubo, K; Brenner, MD; Cullere, X; Saggu, G; Patchen, ML; Bose, N; Mihori, S; Yuan, Z; Lowell, CA; Zhu, C; Mayadas, TN

Mayadas, TN (corresponding author), Brigham & Womens Hosp, Dept Pathol, 75 Francis St, Boston, MA 02115 USA.; Mayadas, TN (corresponding author), Harvard Med Sch, Boston, MA 02115 USA.

CELL REPORTS, 2021; 35 (7):

Abstract

The interaction of the human Fc gamma RIIA with immune complexes (ICs) promotes neutrophil activation and thus must be tightly controlled to avoid dam......

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