Structural basis of human PCNA sliding on DNA

De March, M; Merino, N; Barrera-Vilarmau, S; Crehuet, R; Onesti, S; Blanco, FJ; De Biasio, A

Onesti, S; De Biasio, A (reprint author), Elettra Sincrotrone Trieste SCpA, Struct Biol Lab, I-34149 Trieste, Italy.; Blanco, FJ (reprint author), CIC BioGUNE, Parque Tecnol Bizkaia Edificio 800, Derio 48160, Spain.; Blanco, FJ (reprint author), Ikerbasqu

NATURE COMMUNICATIONS, 2017; 8 ( ):

Abstract

Sliding clamps encircle DNA and tether polymerases and other factors to the genomic template. However, the molecular mechanism of clamp sliding on DNA......

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